Peptides Trapping Dioxins: A Docking-Based Inverse Screening Approach
A rapid and cost-effective computational methodology for designing and rationalizing the selection of small peptides as receptors for dioxin-like compounds was proposed.The backbone of the dioxin Ah receptor binding site was used to design a series of penta- and hexapeptide libraries, with 1400 elements in total.Peptide flexibility was considered a